Annual pruning waste from grapevines in Qazvin province is typically burned for vineyard sanitation purposes, despite possessing significant potential as a cellulosic resource. This research focuses on the optimal utilization of these pruning residues for particleboard production. To this end, a novel proposal for producing particleboard from agricultural waste was introduced, and its economic potential was thoroughly investigated. Laboratory boards were fabricated from this cellulosic material using a completely randomized factorial design with three replications. The experimental variables included two levels of urea-formaldehyde adhesive content (10% and 12%) and three pressing times (4, 5, and 6 minutes). The physical and mechanical properties of the produced boards were measured and subjected to statistical analysis.The results indicated a significant improvement in the boards’ bending strength and Modulus of Elasticity (MOE) with an increase in both adhesive content and pressing time. Furthermore, a linear relationship was observed between adhesive content and the boards’ internal bond (IB) strength. The optimal conditions for internal bond strength were achieved at 12% adhesive content and a 6-minute pressing time. The minimum thickness swelling (TS) of the produced boards was also observed at 12% adhesive usage.All research, laboratory operations, and industrial production aspects were successfully executed by researchers from the Wood and Forest Products Research Department of the Research Institute of Forests and Rangelands as a completed research project. The findings demonstrate a high potential for utilizing this waste to create employment opportunities and optimize processing, which can significantly contribute to the economic sustainability of the grape industry.